The Collaboration of Observational HIV Epidemiological Research Europe (COHERE) was formed in 2005 to pool and harmonize existing longitudinal data on HIV-positive persons collected across Europe to answer key research questions that, in the era of potent combination antiretroviral therapy (cART), could not be addressed adequately by individual cohorts. COHERE uses the HIV Cohorts Data Exchange Protocol (HICDEP), a standardized and validated method of data structure and transfer, to compile data from 40 cohorts of HIV-infected people residing in Europe, representing ~300,000 HIV-positive persons, and over 2 million person-years of follow-up. Mergers of data for approved projects are conducted annually. COHERE compiles data on clinical characteristics, antiretroviral therapy and other medications, HIV seroconversion, opportunistic infections, and laboratory results (CD4-positive T-lymphocyte counts, CD8-positive lymphocytes, viral load, virological and serological tests for other infections, and HIV resistance tests) and socio demographic data. COHERE projects have thus far focused on long-term prognosis, rare outcomes and variations across patient groups, settings and health systems.
The Cohere Collaboration has been described in its International Journal of Epidemiology Cohort Profile.
Contact Information for the Regional Coordinating Centres:
| Copenhagen |
Bordeaux |
| CHIP |
Institut de Santé Publique,d'Epidémiologie et de Développement (ISPED) |
Dorthe Raben, Director of Research Coordination
|
Geneviève Chêne |
University of Copenhagen
CHIP, Department of Infectious
Diseases and Rheumatology
Section 2100, Finsencentret |
Université de Bordeaux - INSERM U1219
146 rue Léo Saignat
F-33076 Bordeaux cedex
France |
| Blegdamsvej 9 |
Tel: +33 557 57 13 92 |
| DK-2100 Copenhagen Ø |
Fax: +33 557 57 11 72 |
Denmark
|
genevieve.chene@isped.u-bordeaux2.fr |
Tel: +45 35 45 57 82
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| dorthe.raben@regionh.dk |
Data Manager:Monique Termote
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| Data Manager:Casper Møller Frederiksen |
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