peer-reviewed Publications 2019

1 Cessation of Cigarette Smoking and the Impact on Cancer Incidence in Human Immunodeficiency Virus-infected Persons: The Data Collection on Adverse Events of Anti-HIV Drugs Study. L Shepherd, L Ryom, M Law, K Petoumenos, C Ingrid Hatleberg, A d’Arminio Monforte, C Sabin, M Bower, F Bonne, P Reiss, S de Wit, C Pradier, R Weber, W el-Sadr, J Lundgren, A Mocroft. On behalf of the D:A:D Study group
Clin Infect Dis. 2019;68(4):650-657. Abstract

2 Benefit of Early versus Deferred Antiretroviral Therapy on Progression of Liver Fibrosis among People with HIV in the START Randomized Trial. Dharan NJ, Neuhaus J, Rockstroh JK, Peters L, Gordin F, Arenas-Pinto A, Emerson C, Marks K, Hidalgo J, Sarmento-Castro R, Stephan C, Kumarasamy N, Emery S, Matthews GV; INSIGHT START Study Group.
Hepatology. 2019;69(3):1135-1150. Epub 2019 Feb 19. Abstract

3 Establishing a hepatitis C continuum of care among HIV/hepatitis C virus-coinfected individuals in EuroSIDA. Amele S, Peters L, Sluzhynska M, Yakovlev A, Scherrer A, Domingo P, Gerstoft J, Viard JP, Gisinger M, Flisiak R, Bhaghani S, Ristola M, Leen C, Jablonowska E, Wandeler G, Stellbrink H, Falconer K, D'Arminio Monforte A, Horban A, Rockstroh JK, Lundgren JD, Mocroft A; EuroSIDA study group.
HIV Med. 2019;20(4):264-273. Abstract

4 Incidence of hepatocellular carcinoma in HIV/HBV-coinfected patients on tenofovir therapy: Relevance for screening strategies. Wandeler, G., Mauron, E., Atkinson, A., Dufour, J-F., Kraus, D., Reiss, P., Peters, L., Dabis, F., Fehr, J., Bernasconi, E., van der Valk, M., Smit, C., Gjærde, L.K., Rockstroh, J., Neau, D., Bonnet, F., Rauch, A., on behalf of the Swiss HIV Cohort Study, Athena Observational Cohort Study, EuroSIDA, ANRS CO3 Aquitaine Cohort
J Hepatol. 2019;71(2):274-280. Epub 2019 Apr 6. Abstract

5 Use of contemporary protease inhibitors Darunavir and risk of incident chronic kidney disease in HIV-positive persons; the D:A:D Study
Lene Ryom, Jens Dilling Lundgren, Peter Reiss,, Ole Kirk, Matthew Law, Mike Ross, Phillip Morlat, Christoph Andreas Fux, Eric Fontas, Stephane De Wit, Antonella d’Arminio Monforte, Wafaa El Sadr, Andrew Phillips, Camilla Ingrid Hatleberg, Caroline Sabin and Amanda Mocroft for the D:A:D Study Group
The Journal of Infectious Diseases 2019. Abstract

6 Serious clinical events in HIV-positive persons with chronic kidney disease (CKD). Ryom L, Lundgren JD, Law M, Kirk O, El-Sadr W, Bonnet F, Weber R, Fontas E, Monforte AD, Phillips A, Reiss P, de Wit S, Hatleberg CI, Sabin C, Mocroft A; D:A:D study group.
AIDS. 2019.  [Epub ahead of print] Abstract

7 Predictors of Ischemic and Hemorrhagic Strokes Among People Living With HIV: The D:A:D International Prospective Multicohort Study
Camilla Ingrid Hatleberg, Lene Ryom, David Kamara, Stephane De Wit, MatthewLaw, Andrew Phillips, Peter Reiss, Antonella D'Arminio Monforte, AmandaMocroft, Christian Pradier, Ole Kirk, Helen Kovari, Fabrice Bonnet, Wafaa El-Sadr, Jens D. Lundgren, CarolineSabin, for the D:A:D Study Group   
EClinicalMedicine Volume 13, P91-100,  2019. Abstract

8 The EuroSIDA study: 25 years of scientific achievements​. K Laut,  O Kirk, J Rockstroh ,A Phillips, B Ledergerber, J Gatell  B Gazzard, A Horban, I Karpov, M Losso, A d’Arminio Monforte, C Pedersen, M Ristola, P Reiss, AU Scherrer, S de Wit, I Aho, LD Rasmussen, V Svedhem, G Wandeler, C Pradier, N Chkhartishvili, R Matulionyte, C Oprea, JD Kowalska, J Begovac, JM Miró, G Guaraldi, R Paredes, D Raben, D Podlekareva, L Peters, JD Lundgren, A Mocroft for the EuroSIDA study.
HIV Med. 2019. Abstract

9 Lymphocyte Count Kinetics, Factors Associated with the End-of-Radiation-Therapy Lymphocyte Count, and Risk of Infection in Patients with Solid Malignant Tumors Treated with Curative-Intent Radiation Therapy. Terrones-Campos C, Ledergerber B, Vogelius IR, Specht L, Helleberg M, Lundgren J.
Int J Radiat Oncol Biol Phys. 2019 Nov 15;105(4):812-823. Abstract

10 Abdominal adipose tissue is associated with alterations in tryptophan-kynurenine metabolism and markers of systemic inflammation in people with HIV. Gelpi M, Ueland PM, Trøseid M, Mocroft A, Lebech AM, Ullum H, Midttun Ø, Lundgren J, Nielsen SD; Copenhagen Comorbidity in HIV Infection (COCOMO) Study.
J Infect Dis. 2019. Abstract

11 Poor Concordance Between Liver Stiffness and Noninvasive Fibrosis Scores in HIV Infection Without Viral Hepatitis. Kirkegaard-Klitbo DM, Bendtsen F, Lundgren J, Nielsen SD, Benfield T; COCOMO study group.
Clin Gastroenterol Hepatol. 2019. Abstract

12 "Risk of de novo or secondary cancer after solid organ or allogeneic haematopoietic stem cell transplantation". Wareham NE, Li Q, Sengeløv H, Da Cunha-Bang C, Gustafsson F, Heilmann C, Perch M, Rasmussen A, Sørensen SS, Mocroft A, Lundgren JD.
J Cancer Res Clin Oncol. 2019;145(12):3125-3135. Abstract

13 A Large-Cohort, Longitudinal Study Determines Precancer Disease Routes across Different Cancer Types. Hu JX, Helleberg M, Jensen AB, Brunak S, Lundgren J.
Cancer Res. 2019; 79(4):864-872. Abstract

14 Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Rodger AJ, Cambiano V, Bruun T, Vernazza P, Collins S, Degen O, Corbelli GM, Estrada V, Geretti AM, Beloukas A, Raben D, Coll P, Antinori A, Nwokolo N, Rieger A, Prins JM, Blaxhult A, Weber R, Van Eeden A, Brockmeyer NH, Clarke A, Del Romero Guerrero J, Raffi F, Bogner JR, Wandeler G, Gerstoft J, Gutiérrez F, Brinkman K, Kitchen M, Ostergaard L, Leon A, Ristola M, Jessen H, Stellbrink HJ, Phillips AN, Lundgren J; PARTNER Study Group.
Lancet. 2019;393(10189):2428-2438. Abstract

15 Acute Lung Injury in Critically Ill Patients: Actin-Scavenger Gelsolin Signals Prolonged Respiratory Failure. Holm FS, Sivapalan P, Seersholm N, Itenov TS, Christensen PH, Jensen JS.
Shock. 2019;52(3):370-377. Abstract

16 Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial. Davey RT Jr, Fernández-Cruz E, Markowitz N, Pett S, Babiker AG, Wentworth D, Khurana S, Engen N, Gordin F, Jain MK, Kan V, Polizzotto MN, Riska P, Ruxrungtham K, Temesgen Z, Lundgren J, Beigel JH, Lane HC, Neaton JD; INSIGHT FLU-IVIG Study Group.
Lancet Respir Med. 2019; 7(11):951-963. Abstract

17 Biomarker-assisted identification of sepsis-related acute liver impairment: a frequent and deadly condition in critically ill patients. Jensen JS, Peters L, Itenov TS, Bestle M, Thormar KM, Mohr TT, Lundgren B, Grarup J, Lundgren JD; Procalcitonin And Survival Study (PASS) Group.
Clin Chem Lab Med. 2019; 57(9):1422-1431. Abstract

18 COPD exacerbations: the impact of long versus short courses of oral corticosteroids on mortality and pneumonia: nationwide data on 67 000 patients with COPD followed for 12 months. Sivapalan P, Ingebrigtsen TS, Rasmussen DB, Sørensen R, Rasmussen CM, Jensen CB, Allin KH, Eklöf J, Seersholm N, Vestbo J, Jensen JS.
BMJ Open Respir Res. 2019;6(1):e000407. Abstract

19 Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials. Chemaly RF, Chou S, Einsele H, Griffiths P, Avery R, Razonable , Mullane KM, Kotton C, Lundgren J, Komatsu TE, Lischka P, Josephson F, Douglas CM, Umeh O, Miller V, Ljungman P; Resistant Definitions Working Group of the Cytomegalovirus Drug Development Forum.
Clin Infect Dis. 2019;68(8):1420-1426. Abstract

20 Effect Estimates in Randomized Trials and Observational Studies: Comparing Apples With Apples. Lodi S, Phillips A, Lundgren J, Logan R, Sharma S, Cole SR, Babiker A, Law M, Chu H, Byrne D, Horban A, Sterne JAC, Porter K, Sabin C, Costagliola D, Abgrall S, Gill J, Touloumi G, Pacheco AG, van Sighem A, Reiss P, Bucher HC, Montoliu Giménez A, Jarrin I, Wittkop L, Meyer L, Perez-Hoyos S, Justice A, Neaton JD, Hernán MA; INSIGHT START Study Group and the HIV-CAUSAL Collaboration.
Am J Epidemiol. 2019;188(8):1569-1577. Abstract

21 Efficacy of seven and fourteen days of antibiotic treatment in uncomplicated Staphylococcus aureus bacteremia (SAB7): study protocol for a randomized controlled trial. Thorlacius-Ussing L, Andersen CØ, Frimodt-Møller N, Knudsen IJD, Lundgren J, Benfield TL.
Trials. 2019;20(1):250. Abstract

22 Epidemiology of bloodstream infections in patients with chronic lymphocytic leukemia: a longitudinal nation-wide cohort study. Andersen MA, Moser CE, Lundgren J, Niemann CU.
Leukemia. 2019;33(3):662-670. Abstract

23 Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing. Ilett EE, Jørgensen M, Noguera-Julian M, Daugaard G, Murray DD, Helleberg M, Paredes R, Lundgren J, Sengeløv H, MacPherson C.
Sci Rep. 2019;9(1):13351. Abstract

24 Immune function as predictor of infectious complications and clinical outcome in patients undergoing solid organ transplantation (the ImmuneMo:SOT study): a prospective non-interventional observational trial. Drabe CH, Sørensen SS, Rasmussen A, Perch M, Gustafsson F, Rezahosseini O1, Lundgren JD, Ostrowski SR, Nielsen SD.
BMC Infect Dis. 2019;19(1):573. Abstract

25 Incidence Rates and Risk Factors of Clostridioides difficile Infection in Solid Organ and Hematopoietic Stem Cell Transplant Recipients. Ilett EE, Helleberg M, Reekie J, Murray DD, Wulff SM, Khurana MP, Mocroft A, Daugaard G, Perch M, Rasmussen A, Sørensen SS, Gustafsson F, Frimodt-Møller N, Sengeløv H, Lundgren J.
Open Forum Infect Dis. 2019;6(4). Abstract

26 Incomplete ART adherence is associated with higher inflammation in individuals who achieved virologic suppression in the START study. Castillo-Mancilla JR, Phillips AN, Neaton JD, Neuhaus J, Sharma S, Baker JV, Collins S, Mannheimer S, Pett S, Touzeau-Römer V, Polizzotto MN, Lundgren JD, Gardner EM; INSIGHT START Study Group.
J Int AIDS Soc. 2019;22(6). Abstract

27 Increased Risk of Anemia, Neutropenia, and Thrombocytopenia in People With Human Immunodeficiency Virus and Well-Controlled Viral Replication. Akdag D, Knudsen AD, Thudium RF, Kirkegaard-Klitbo DM, Nielsen C, Brown P, Afzal S, Nordestgaard BG, Lundgren J, Nielsen SD.
J Infect Dis. 2019;220(11):1834-1842. Abstract

28 Long-lasting alterations in adipose tissue density and adiponectin production in people living with HIV after thymidine analogues exposure. Gelpi M, Knudsen AD, Larsen KB, Mocroft A, Lebech AM, Lindegaard B, Lundgren J, Kofoed KF, Nielsen SD; Copenhagen Comorbidity in HIV Infection (COCOMO) Study.
BMC Infect Dis. 2019;19(1):708. Abstract

29 Mortality in critical illness: The impact of asymmetric dimethylarginine on survival-A systematic review and meta-analysis. Mortensen KM, Itenov TS, Hansen MB, Hvid K, Lundstrøm LH, Bestle MH.
Acta Anaesthesiol Scand. 2019;63(6):708-719. Abstract

30 Prevalence and risk factors of prolonged QT interval and electrocardiographic abnormalities in persons living with HIV. Knudsen AD, Kofoed KF, Gelpi M, Sigvardsen PE, Mocroft A, Kühl JT, Fuchs A, Køber L, Nordestgaard BG, Benfield T, Graff C, Skov MW, Lundgren J, Nielsen SD; Copenhagen Comorbidity in HIV Infection (COCOMO) Study.
AIDS. 2019;33(14):2205-2210. Abstract

31 Prevalence of impaired renal function in virologically suppressed people living with HIV compared with controls: the Copenhagen Comorbidity in HIV Infection (COCOMO) study. Petersen N, Knudsen AD, Mocroft A, Kirkegaard-Klitbo D, Arici E, Lundgren J, Benfield T, Oturai P, Nordestgaard BG, Feldt-Rasmussen B, Nielsen SD, Ryom L.
HIV Med. 2019;20(10):639-647. Abstract

32 Prior exposure to thymidine analogs and didanosine is associated with long-lasting alterations in adipose tissue distribution and cardiovascular risk factors. Gelpi M, Afzal S, Fuchs A, Lundgren J, Knudsen AD, Drivsholm N, Mocroft A, Lebech AM, Lindegaard B, Kühl JT, Sigvardsen PE, Køber L, Nordestgaard BG, Kofoed KF, Nielsen SD.
AIDS. 2019;33(4):675-683. Abstract

33 Pseudomonas aeruginosa and risk of death and exacerbations in patients with chronic obstructive pulmonary disease: an observational cohort study of 22 053 patients. Eklöf J, Sørensen R, Ingebrigtsen TS, Sivapalan P, Achir I, Boel JB, Bangsborg J, Ostergaard C, Dessau RB, Jensen US, Browatzki A, Lapperre TS, Janner J, Weinreich UM, Armbruster K, Wilcke T, Seersholm N, Jensen JUS.
Clin Microbiol Infect. 2019. pii: S1198-743X(19)30336-2. Abstract

34 Risk factors for antiretroviral therapy (ART) discontinuation in a large multinational trial of early ART initiators. Bansi-Matharu L, Rodriguez Loria G, Cole SR, Mugerwa H, Vecino I, Lundgren J, Pulik P, Smith C, Phillips AN; INSIGHT START Study Group.
AIDS. 2019;33(8):1385-1390. Abstract

35 Risk Factors for Failure of Primary (Val)ganciclovir Prophylaxis Against Cytomegalovirus Infection and Disease in Solid Organ Transplant Recipients. Khurana MP, Lodding IP, Mocroft A, Sørensen SS, Perch M, Rasmussen A, Gustafsson F, Lundgren JD.
Open Forum Infect Dis. 2019;6(6). Abstract

36 Risk Factors for Low CD4+ Count Recovery Despite Viral Suppression Among Participants Initiating Antiretroviral Treatment With CD4+ Counts > 500 Cells/mm3: Findings From the Strategic Timing of AntiRetroviral Therapy (START) Trial. Boatman JA, Baker JV, Emery S, Furrer H, Mushatt DM, Sedláček D, Lundgren JD, Neaton JD; INSIGHT START Study Group.
J Acquir Immune Defic Syndr. 2019;81(1):10-17. Abstract

37 Risks and benefits of dolutegravir-based antiretroviral drug regimens in sub-Saharan Africa: a modelling study. Phillips AN, Venter F, Havlir D, Pozniak A, Kuritzkes D, Wensing A, Lundgren JD, De Luca A, Pillay D, Mellors J, Cambiano V, Bansi-Matharu L, Nakagawa F, Kalua T, Jahn A, Apollo T, Mugurungi O, Clayden P, Gupta RK, Barnabas R, Revill P, Cohn J, Bertagnolio S, Calmy A.
Lancet HIV. 2019;6(2):e116-e127. Abstract

38 Association Between Single-Nucleotide Polymorphisms in HLA Alleles and Human Immunodeficiency Virus Type 1 Viral Load in Demographically Diverse, Antiretroviral Therapy-Naive Participants From the Strategic Timing of AntiRetroviral Treatment Trial. Ekenberg C, Tang MH, Zucco AG, Murray DD, MacPherson CR, Hu X, Sherman BT, Losso MH, Wood R, Paredes R, Molina JM, Helleberg M, Jina N, Kityo CM, Florence E, Polizzotto MN, Neaton JD, Lane HC, Lundgren JD.
J Infect Dis. 2019;220(8):1325-1334. Abstract

39 The Effect of Interrupted/Deferred Antiretroviral Therapy on Disease Risk: A SMART and START Combined Analysis. Borges ÁH, Neuhaus J, Sharma S, Neaton JD, Henry K, Anagnostou O, Staub T, Emery S, Lundgren JD; INSIGHT SMART; START Study Groups.
J Infect Dis. 2019;219(2):254-263. Abstract

40 Identifying cross-disease components of genetic risk across hospital data in the UK Biobank. Cortes A, Albers PK, Dendrou CA, Fugger L, McVean G.
Nature Genetics, 2019. Abstract

41 Uptake and effectiveness of two-drug compared with three-drug antiretroviral regimens among HIV-positive individuals in Europe. Neesgaard B, Pelchen-Matthews A, Ryom L, Florence E, Peters L, Roen A, Svedhem V, Clarke A, Benfield T, Mitsura V, Moreno S, Beniowski M, Begovac J, Matulionyte R, Trofimova T, Elbirt D, Kundro M, Vullo V, Behrens G, Staub T, Ragone L, Vannappagari V, Lundgren J, Mocroft A; EuroSIDA study.
AIDS. 2019;33(13):2013-2024. Abstract

42 Improving the evidence for indicator condition guided HIV testing in Europe: Results from the HIDES II Study – 2012 – 2015. Raben D, Sullivan AK, Mocroft A, Kutsyna G, Hadžiosmanović V, et al., on behalf of the HIDES Study Group.
PLOS ONE, 2019. Article

43 HIV testing strategies outside of health care settings in the European Union (EU)/European Economic Area (EEA): a systematic review to inform European Centre for Disease Prevention and Control guidance. Croxford S, Tavoschi L, Sullivan AK, Combs L, Raben D, Delpech V, Jakobsen SF, Amato-Gauci AJ, Desai S.
HIV Medicine, 2019. Article

44 HIV testing strategies employed in health care settings in the European Union/European Economic Area (EU/EEA): evidence from a systematic review. Desai S, Tavoschi L, Sullivan AK, Combs L, Raben D, Delpech V, Jakobsen SF, Amato‐Gauci AJ, Croxford S
HIV Medicine, 2019. Article

45 Going new ways to end HIV: reaching men who have sex with men through a community, business, and public health partnership to increase HIV testing in Europe. Combs L, Daamen C, Kifetew C
RECS. Suplemento 2, 2019.Comunicación y VIH. Article

46 The Consensus Hepatitis C Cascade of Care: Standardized Reporting to Monitor Progress Toward Elimination. Safreed-Harmon K, Blach S, Aleman S, Bollerup S, Cooke G, Dalgard O, Dillon JF, Dore GJ, Duberg AS, Grebely J, Boe Kielland K, Midgard H, Porter K, Razavi H, Tyndall M, Weis N, Lazarus JV.
Clin Infect Dis. 2019; 69(12):2218-2227. Abstract