Template for Submission of Research Concepts for Consideration by the D:A:D Steering Committee
The D:A:D study is a prospective multi-cohort study of HIV-positive persons under active follow-up.
The study was established in 1999 to assess the incidence of myocardial infarction in HIV-positive persons receiving anti-retroviral therapy. Since then the research agenda has expanded to include other clinical endpoints such as stroke, diabetes, cancers, end-stage liver and renal disease and mortality.
The D:A:D Steering Committee (SC) consists of cohort representatives, central statisticians, member from the HAART Oversight Committee and the D:A:D chair.
The SC encourages the submission of concepts for new research projects. Concepts can be submitted for review by the D:A:D SC using the template below
Once submitted the research concept will undergo review by the D:A:D SC for evaluation of the following:
- Scientific relevance
- Relevance to the D:A:D Study
- Design and feasibility
- Statistical power and feasability
- Overlap with already approved projects
Upon completion of the review, feedback will be provided to the
proposer(s). In some circumstances, a revision of the concept may be requested.
If the concept is approved for implementation, a writing group will be established consisting of the proposers (up to 3 persons that were centrally involved in the development of the concept) and members of the D:A:D Steering Committee (or other appointed cohort representatives) Statistical department and Coordinating Center.
All persons involved in the process of reviewing these research concepts are bound by confidentiality.