START Publications 2019

Benefit of early versus deferred antiretroviral therapy on progression of liver fibrosis among people with HIV in the START randomized trial. Dharan NJ, Neuhaus J, Rockstroh JK, Peters L, Gordin F, Arenas-Pinto A, Emerson C, Marks K, Hidalgo J, Sarmento-Castro R, Stephan C, Kumarasamy N, Emery S, Matthews GV for the INSIGHT START Study Group.
Hepatology 2019; 69(3):1135-1150. Abstract & Article

Associations between baseline biomarkers and lung function in HIV-positive individuals in the START pulmonary substudy. MacDonald DM, Zanotto AD, Collins G, Baker JV, Czarnecki M, Loiza E, Nixon DE, Papastamopoulos V, Wendt CH, Wood R, Kunisaki KM for the INSIGHT START Pulmonary Substudy Group. 
AIDS 2019; 33:655-664. Abstract & Article

Risk factors for antiretroviral therapy (ART) discontinuation in a large multinational trial of early ART initiators. Bansi-Matharu L, Rodriguez Loria G, Cole SR, Mugerwa H, Vecino I, Lundgren J, Pulik P, Smith C, Phillips AN; INSIGHT START Study Group.
AIDS. 2019;33(8):1385-1390. Abstract

Risk Factors for Low CD4+ Count Recovery Despite Viral Suppression Among Participants Initiating Antiretroviral Treatment With CD4+ Counts > 500 Cells/mm3: Findings From the Strategic Timing of AntiRetroviral Therapy (START) Trial. Boatman JA, Baker JV, Emery S, Furrer H, Mushatt DM, Sedláček D, Lundgren JD, Neaton JD; INSIGHT START Study Group.
J Acquir Immune Defic Syndr. 2019;81(1):10-17. Abstract

The Effect of Interrupted/Deferred Antiretroviral Therapy on Disease Risk: A SMART and START Combined Analysis. Borges ÁH, Neuhaus J, Sharma S, Neaton JD, Henry K, Anagnostou O, Staub T, Emery S, Lundgren JD; INSIGHT SMART; START Study Groups.
J Infect Dis. 2019;219(2):254-263. Abstract

Incomplete ART adherence is associated with higher inflammation in individuals who achieved virologic suppression in the START study. Castillo-Mancilla JR, Phillips AN, Neaton JD, Neuhaus J, Sharma S, Baker JV, Collins S, Mannheimer S, Pett S, Touzeau-Römer V, Polizzotto MN, Lundgren JD, Gardner EM; INSIGHT START Study Group.
J Int AIDS Soc. 2019;22(6). Abstract

 Effect Estimates in Randomized Trials and Observational Studies: Comparing Apples With Apples. Lodi S, Phillips A, Lundgren J, Logan R, Sharma S, Cole SR, Babiker A, Law M, Chu H, Byrne D, Horban A, Sterne JAC, Porter K, Sabin C, Costagliola D, Abgrall S, Gill J, Touloumi G, Pacheco AG, van Sighem A, Reiss P, Bucher HC, Montoliu Giménez A, Jarrin I, Wittkop L, Meyer L, Perez-Hoyos S, Justice A, Neaton JD, Hernán MA; INSIGHT START Study Group and the HIV-CAUSAL Collaboration.
Am J Epidemiol. 2019;188(8):1569-1577. Abstract