The following substudies have been successfully completed and are now closed. 

Informed Consent substudy - Closed

Monitoring substudy - Closed

Genomics substudy - Closed

Neurology substudy - Closed

Arterial Elasticity substudy - Closed

Pulmonary substudy - Closed

Bone Mineral Density substudy - Closed

Liver Fibrosis substudy - Closed